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KMID : 0383119600080010001
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Journal of Aerospace Medicine
1960 Volume.8 No. 1 p.1 ~ p.15
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Studies on the Tolerance, of Living Bodies 1 to Carbon Monoxide
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Abstract
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PART I : Tolerance of Mice to Carbon Monoxide
When fuels or other carboniferous m aterials are burnt, the presence of CO, and of CO is noted and human being, has more or less opportunities to be exposed to ambient CO. Moreover as Wilks & Clark` (8) stated, mechanical failures and some physiological impairments of the, crewmen might be. considered as factors contributing to recently increasing accidents of jet type aircraft. The latter has been thought to be due to toxic gases, within the confines of the personnel compartments of the aircaf t. These toxic gases may be originated from
a) thermal disintegration of organic materials such as electrical installations within the confines of the cockpit.
b)overheating of oils or lubricauts in association with the pressurization-ventilating system and
c) entrance of combustion gases through the ventilating system. Of these gases, CO is probably the most important. Particulary in Korea, as the briquette has recently become widely used, the CO concentration in kitchens and in living rooms is increased so greatly that it should be given a special consideration.
Flury and Forster(13) reported that mice survived in 0.1? of CO, while Bock(13) observed that they died following the exposure to 0.2 to 0.5? of CO.
In the present investigation, the author studied the relationship between the CO concentration and tolerance in 300 mice. The tolerance of animals to a given CO consent ration is evaluated on the basis of the length of time to arrest the respiration; as judged by the visual inspection.
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KEYWORD
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